Sunday, July 03, 2005

The Lyon hypothesis and the maintenance of pregnancy

The Lyon hypothesisis the suggestion that female mammals, including women, have one of their two X chromosomes randomly inactivated in each cell. I wonder if this is related to the need for female mammals to carry offspring inside their bodies during pregnancy but not reject them as immunologically different. If the female is herself a genetic mosaic, she may be more tolerant of a wider range of immune types in her foetus.

This article may be relevant.



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